Increasing blood flow facilitates the supply of nutrients and oxygen to the site of wounds, and results in tissue healing. Innocuous heat stimulus increases the tissue temperature, resulting in increased blood flow and tissue metabolism. Thermal therapy is also well known to be useful for treating pain in humans.
#Hot packs for pain manual
However, pain induced by joint movement in physically inactive patients may limit their exercise or the manual therapy they can receive. These results suggest that NGF may play a pivotal role in the skin and muscular mechanical hyperalgesia induced by physical inactivity.Įxercise and manual therapy have been reported to be highly effective analgesic therapies in clinical studies. Furthermore, we have reported that physical inactivity increases the amount of NGF protein in the gastrocnemius muscle. An increase in NGF protein in the plantar skin and the up-regulation of NGF positive neurons in the dorsal root ganglions (DRGs) have also been shown to be induced by cast immobilization. NGF is known to be involved in cutaneous tactile allodynia and muscular mechanical hyperalgesia in some disease states. Macrophages release nerve growth factor (NGF). Muscular atrophy caused by cast immobilization induces the infiltration of macrophages in the skeletal muscle. These studies suggest that some physically inactive conditions induce some pain conditions. In other physically inactive conditions, casting also induced disuse atrophy, joint contracture and cutaneous mechanical and/or cold hyperalgesia in human and animal studies. A recent study showed that long-term bed rest induced disuse atrophy, muscle damage, and pain. However, this may cause undesirable side effects. Persons who have health problems treated by casting or bed rest often become physically inactive.
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